Advancing excellence in laboratory medicine for better healthcare worldwide

Committee on Clinical Applications of Cardiac Bio-Markers (C-CB)

Membership

Name Position Country Term Time in Office
F. Apple Chair US 1st 2017 01 - 2019 12
P. Kavsak Member CA 1st 2017 01 - 2019 12
G. Lefevre Member FR 1st 2017 01 - 2019 12
K. Pulkki Member FI 1st 2017 01 - 2019 12
A. Saenger Member US 1st 2017 01 - 2019 12
R. Body Member UK 1st 2017 01 - 2019 12
SPC Lam Member SG 1st 2017 01 - 2019 12
T. Omland Member NO 1st 2017 01 - 2019 12
P. Collinson Consultant UK    
A. Jaffe Consultant US    
J. Ordoñez-Llanos Consultant ES    

Terms of Reference

  • Education; Established and novel cardiac biomarkers
  • Biochemistry of cardiac biomarkers
  • Clinical use of cardiac biomarkers: risk stratification, diagnostics, therapy
  • Laboratory issues on cardiac biomarkers: 99th percentiles, delta values, biological variation, quality specifications of assays

Current Projects

  • Development of educational materials about high-sensitivity, contemporary and point of care cardiac troponin assay use in clinical practice.
  • Development of educational materials about natriuretic peptide assay use in clinical practice
  • Development of educational expert opinion materials in collaboration with The Academy of the AACC on the use of cardiac troponin in coronary disease
  • Updating cardiac troponin and natriuretic peptide assay tables by both manufacturer claims and from peer-reviewed literature
  • Distribution of educational posters and mouse-pads addressing high sensitivity cardiac troponin assays at IFCC meetings in 2017

 

31st January, 2019

On behalf of the members of the IFCC Committee on Clinical Applications of Cardiac Bio-Markers (C-CB), we post our first 2019 set of tables, updating the analytical characteristics of contemporary, point of care (POC) and high sensitivity (hs) cardiac troponin I and T assays; as provided by the manufacturer to the C-CB.

Please note that these tables represent information that were completed by the manufacturer. If after posting, the manufacturer notes any error, please email me ASAP, so these can be corrected. Also note that manufacturers may have submitted assays they claim to be ‘high sensitivity’ that do not meet the IFCC requirements of: a) ≤10% CV at the 99th percentile and b) ≥50% measurable concentrations ≥ LoD (Apple FS, Jaffe AS, Collinson P, Mockel M, Ordonez-Llanos J, Lindahl B, Hollander J, Plebani M, Than M, Chann MHM, on behalf of the IFCC Task Force on Clinical Applications of Cardiac Bio-Markers. IFCC educational materials on selected analytical and clinical applications of high-sensitivity cardiac troponin assays. Clin Biochem 2015: 2015;48:201-203).

As a Committee we have not altered their information.

It is the plan of the IFCC C-CB to update these tables every 6 months. Therefore, we encourage both industry and investigators to email me any new or updated assay information based on research publications or regulatory approval package inserts, to assist in our table updates.

Peace

Fred Apple PhD, Chair IFCC C-CB

apple004@umn.edu

 Click on the titles to download the documents:

 Tables posted 31st January 2019:

 

Tables posted 26 July 2018:

 

For older versions of above tables and further resources, visit: Resources and Downloads

 

 

List of Corresponding Members, nominated by National Societies

Name

Full and Affiliate Member Societies
Caroline Le Goff Royal Belgian Society of Laboratory Medicine (RBSLM)
Galina Zemtsovskaja Estonian Society of Laboratory Medicine
Hannsjoerg Baum Deutsche Gesellschaft für Klinische Chemie und Laboratoriumsmedizin e.V. (DGKL)
Monica Mion Italian Society of Clinical Chemistry and Clinical Molecular Biology (SIBioC)
Hiroshi Yoshida Japan Society of Clinical Chemistry (JSCC)
Dovile Karciauskaite Lithuanian Society of Laboratory Medicine
Akinosun Bayo Association of Clinical Chemists Nigeria (ACCN)
Lakminda Thilakarathna Association for Clinical Biochemistry, Sri Lanka
Aylin  Hakligor

Turkish Biochemical Society (TBS)

List of Corresponding Members, nominated by Corporate Members

Name Corporate members
Tricia Ravalico ABBOTT Laboratories
Adam Moss ABBOTT APOC
Lindsay Sun BECKMAN COULTER
Geert Jannes FUJIREBIO Europe
Jakob Eriksen RADIOMETER
Kalen Olson SIEMENS Healthineers


Corporate Members Support

Corporate members LEVEL SUPPORT
ABBOTT PLATINUM LEVEL SUPPORT
ALERE CRYSTAL LEVEL SUPPORT
ORTHO CLINICAL DIAGNOSTICS GOLD LEVEL SUPPORT
RADIOMETER BRONZE LEVEL SUPPORT
SIEMENS Healthineers GOLD LEVEL SUPPORT
ROCHE SILVER LEVEL SUPPORT


List of addresses

Chair

Dr Fred APPLE
Hennepin County Medical Center
Professor, Laboratory Medicine and Pathology
University of Minnesota - School of Medicine
701 Park Avenue Clinical Labs P4
Minneapolis MN 55415 US
Tel.: +1  612 873 3324
email: apple004@umn.edu 

Members

 

Dr Peter KAVSAK
McMaster University and Hamilton Health Sciences
Juravinski Hospital and Cancer Center
711 Concession Rd
L8V 1C3 Hamilton - CA

Dr Guillaume LEFEVRE
Biochimie & Hormonologie
Hôpital Tenon  AP-HP
Hôpitaux Universitaires de l’Est Parisien (HUEP)
4, rue de la Chine  75970 PARIS CEDEX 20 - FR

Dr Kari PULKKI
Department of Clinical Chemistry,
University of Eastern Finland and Eastern Finland Laboratory Centre,
PO Box 1627,
FI-70211 Kuopio, Finland

Dr Amy SAENGER 
University of Minnesota
Department of Laboratory Medicine and Pathology
425 Delaware St. SE, Mayo Building MMC609
Minneapolis, MN 55455, US

Dr Richard BODY
Emergency Medicine Research Office,
Emergency Department,
Manchester Royal Infirmary,
Oxford Road,
Manchester,
M13 9WL, UK
Dr Su Ping Carolyn LAM
National Heart Centre Singapore
SingHealth Duke-NUS Cardiovascular Academic Clinical Programme
and Department of Cardiology
5 Hospital Drive
Singapore 169609 - SG

 

Dr Torbjørn OMLAND
Akershus Universitetssykehus
1478 Lørenskog - NO

 

Consultants

 

Dr. Paul O. COLLISON
Department of Chemical Pathology
2nd Floor Jenner Wing
St George's Hospital
Blackshaw Road
London SW17 0QT UK
Tel.: +44  208 725 5934 

Dr. Allan JAFFE
Cardiovascular Division, Gonda 5
Mayo Clinic
200 First Street SW
Rochester - MN 55905
USA 
Tel.: +1 507 284 1648

Dr. Jordi ORDÓÑEZ-LLANOS
Senior Consultant, Biochemistry Dept.
Hospital de Sant Pau
Professor of Clinical Biochemistry
Universitat Autònoma
Barcelona - Spain
Tel.: +34 935537359

 
 
Website developed by Insoft Digital