Task Force on Pharmacogenetics (Integrated Project) - (TF-PG)

Membership

 

Name Position Country Term Time in Office
R. Van Schaik Chair NL 2nd 2011 01 - 2013 12
M. Ferrari Member IT 2nd 2011 01 - 2013 12
H. Guchelaar Member NL 2nd 2011 01 - 2013 12
M. Neumaier Member DE 2nd 2011 01 - 2013 12
M. Pirmohamed Member UK 2nd 2011 01 - 2013 12

Aims

The aim of the Task Force is to facilitate integration of pharmacogenetic testing into routine diagnostics at tde appropriate quality standards.

Objectives

  1. Obtain information on the potential clinical utility of specific pharmacogenetic tests
  2. Obtain information on current perception of genetic variants to be tested
  3. Obtain information on clinical recommendations based on the pharmacogenetic test results from the clinical disciplines involved.
  4. Discuss and weigh the information obtained.
  5. Prepare guiding documents, with participation of the clinical disciplines involved, per drug/gene combination for pharmacogenetic testing, addressing who to test, how to test, how to interpret and how to report.
  6. Identify Pharmacogenetics Expert Labs, in collaboration with the Committee for Molecular Diagnostics.

Delivery

  1. Network of pharmacogenetic experts from in- and outside Clinical Chemistry.
  2. Network of specific contact persons within the relevant clinical disciplines.
  3. Guidance documents: TPMT testing and 6-mercaptopurine/azathioprine, CYP2C19 testing and clopidogrel, CYP2D6 testing and tamoxifen.
  4. Presentation of ongoing work of IFCC TF-PG in presentations and posters at different conferences.

Accountability

The Task Force is directly responsible to tde EB through the President.

List of Addresses

Dr. Ron VAN SCHAIK
Department of Clinical Chemistry
Erasmus University Medical Centre Gavendijkwal 230,
's Gravendijkwal 230
3015 CE Rotterdam
The Netherlands
Tel: +31 10 70 33119
Fax: +31 10 43 67894

Prof. Maurizio FERRARI
Dept. Clinical Molecular Biology and
Cytogenetics
Università Vita-Salute San Raffaele
Via Olgetina, 60
20132 Milano
Italy
Tel: +39 02 2643 2303
Fax: +39 02 2643 2640

Prof. Henk-Jan GUCHELAAR
Dept. Clinical Pharmacy and Toxicology
Leiden University Medical Centre
P.O. Box 9600
2300 RC Leiden
The Netherlands
Tel: +31 71 526 2790
Fax: +31 71 524 2801

Prof. Michael NEUMAIER
Medical Faculty Mannheim
University of Heidelberg
University Hospital Mannheim
Theodor-Kutzer-Ufer 1-3
D-68167 Mannheim
Germany
Tel: +49 621 383 2222
Fax: +49 621 383 3819

Prof. Munir PIRMOHAMED
Dept. Pharmacology
tde University of Liverpool
Ashton Street
Liverpool, L69 3GE
United Kingdom
Tel: +44 151 794 5549
Fax: +44 151 794 5540