New eAcademy JCTLM webinars on Standardization and Harmonization
Published: Wednesday, May 24, 2017
Trueness of measurement results is crucial e.g. to ensure that well-functioning treatment is not changed unnecessarily when samples from the patient are measured in different laboratories over time, in order to share common reference intervals, decision limits and guidelines between measurement methods and for the ability to compare results from research studies over time.
Standardization is about identifying the most appropriate reference materials and reference measurement procedures to make sure that different and laboratories around the globe measure the same concentrations in the same sample today and in the years to come. Standardisation is, however, not always possible. Fortunately, harmonization is always possible comparing measurement results using commutable samples, preferably natural patient samples and adjusting calibrations if needed.
Standardization is preferable to harmonization since it includes mechanisms for maintaining stability during extended periods of time whereas harmonization represents consensus processes primarily valid in the time when the harmonization process is performed.
Both webinare are by Prof Elvar Theodorsson - Department of Clinical and Experimental Medicine (IKE) / Division of Microbiology and Molecular Medicine (MMM), Linköping University, Sweden.