Advancing excellence in laboratory medicine for better healthcare worldwide

Clinical Quantitative Mass Spectrometry Proteomics (WG-cMSP)



Name Position Country Term Time in Office
S.  Lehmann Chair FR 2nd 2014 01 - 2016 12
E.O.  Agbedana Member NG    
Y.  Ando Member JP    
C.  Brede Member NO    
U.  Ceglarek Member DE    
J.A.  Cocho Member ES    
V. Delatour Member FR    
M.  Glückmann Member DE    
Y.  Gong Member CA    
D.  Hochstrasser Member CH    
A.  Hoofnagle Member US    
BE.  Krastin Member US    
A.  Urbani Member IT


Terms of Reference

  • To define appropriate operating procedures to perform quantitative mass spectrometry analyses for peptides and proteins from biological fluids.
  • To evaluate the specification and the need for reference materials for quantitative proteomics applied to clinical biology.
  • To design of a Quality Assurance / Quality Control (QA/QC) Program and to select a small series of analytes to be thesubject of a future multi-site validation study.
  • To test the implementation in clinical laboratories of quantitative mass spectrometry analyses for peptides and proteins, using the examples of hepcidin and apolipoproteins.

Current Projects

  • Evaluate different procedures to collect, fractionate/enzymatic digest biological samples prior to quantitative mass spectrometry analysis.
  • Evaluate the multi-site implementation of different quantitative mass spectrometry analysis including: the detection of hepcidin and the multiplex detection of proteins in blood, with a specific focus on apolipoproteins.
  • Coordination with other proteomics intiatives (HUPO/EuPA, FP7.. ) in particular regarding mass spectrometry based quantitative assays.


List of Corresponding Members, nominated by National Societies

Name Full and Affiliate Member Societies
Daniel Teupser Deutsche Vereinte Gesellschaft für Klinische Chemie und Laboratoriumsmedizin e.V. (DGKL)
Dovile Karciauskaite Lithuanian Society of Laboratory Medicine
Tosin Soyinka Association of Clinical Chemists Nigeria (ACCN)
Sedat Abusoglu Turkish Biochemical Society (TBS)
Bernardina Rivero Asociación Bioquímica Uruguaya (ABU)

Working Group Chairs'  contact

Prof. Sylvain LEHMANN
CHU de Montpellier - Hôpital St. Eloi
Institut de Recherches en Biothérapie (IRB)
Biochimie - Protéomique Clinique
80, av A. Fliche
34295 Montpellier Cedex 5
Tel: +33 04 67 33 71 23 / +33 04 67 33 71 24
Fax: +33 04 67 33 69 21

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