Advancing excellence in laboratory medicine for better healthcare worldwide

Immunosuppressive Drugs (WG-ID)


Name Position Country Term Time in Office
C. Seger Chair CH 1st 2018 01 - 2020 12
M.J. Barten Member DE
S. Bergan         Member NO
M. Brunet Member ES
U. Christians Member US
B. de Winter Member NL
L. Elens Member BE
D. Grote-Koska Member DE
V. Haufroid Member BE
A. Henrion Member DE
D.W. Holt Member UK
P.K. Kunicki Member PL
L. Langman Member US
S. Masuda Member JP
D. Moes Member NL
T. Pawiński Member PL
L.M. Shaw Member US
M. Shipkova Member DE
N. Torre Vethe Member NO
T.  van Gelder Member NL
M. Vogeser Member DE
P. Wallemacq Member BE
E. Wieland Member DE


Terms of Reference

  • The WG is devoted to the establishment of candidate reference procedures and reference materials for immunosuppressive drugs (ISDs) as cyclosporine, sirolimus, tacrolimus, everolimus, and mycophenolic acid (MPA). Demonstration of the current state of the art in ISD – TDM by measurement comparison will define the need for harmonization or – if feasible – standardization of measurement services

 Current projects

  • Regulatory framework :
    • Establish and communicate the regulatory framework which allows submitting to the JCTLM reference materials, measurement methods and measurement services established within the WG-ID.
  • Measurement comparison initiative aimed to assess the state of art in ISD TDM:
    • Baseline assessment including method comparability.
    • Influence of secondary reference materials on method comparability.
  • Production of reference materials to be listed in the JCTLM database:
    • Characterization of primary reference materials.
    • Production of primary reference materials.
    • Characterization and production of secondary reference materials.
  • Establishment of reference methods to be listed in the JCTLM database:
    • Design and validation of a candidate reference method by at least two to three partner institutions.
  • Establishing reference procedures:
    • Establishment of a reference laboratory network.
    • Establishment of a reference measurement service network.


Working Group Chair's contact

PD Dr. Christoph SEGER
Head of Department
Special Chemistry and R & D
labormedizinisches zentrum Dr Risch
Lagerstrasse 30 - 9470 Buchs SG - CH
Wuhrstrasse 14 – 9490 Vaduz – FL
Tel: +41 058 523 31 50 - +41 058 523 31 99



Website developed by Insoft Digital