Committee on Clinical Applications of Cardiac Bio-Markers (C-CB)
Membership
| Name | Position | Country | Term | Time in Office |
| F. Apple | Chair | US | 2nd | 2020 01 - 2022 12 |
| P. Kavsak | Member | CA | 2nd | 2020 01 - 2022 12 |
| O. Hammarsten | Member | SE | 1st | 2020 01 -2022 12 |
| A. Saenger | Member | US | 2nd | 2020 01 - 2022 12 |
| R. Body | Member | UK | 2nd | 2020 01 - 2022 12 |
| SPC Lam | Member | SG | 2nd | 2020 01 - 2022 12 |
| P. Collinson | Consultant | UK | ||
| A. Jaffe | Consultant | US | ||
| J. Ordoñez-Llanos | Consultant | ES | ||
| T. Omland | Consultant | NO |
Terms of Reference
- Education; Established and novel cardiac biomarkers
- Biochemistry of cardiac biomarkers
- Clinical use of cardiac biomarkers: risk stratification, diagnostics, therapy
- Laboratory issues on cardiac biomarkers: 99th percentiles, delta values, biological variation, quality specifications of assays
Current Projects
- Development of educational materials about high-sensitivity, contemporary and point of care cardiac troponin assay use in clinical practice.
- Development of educational materials about natriuretic peptide assay use in clinical practice
- Development of educational expert opinion materials in collaboration with The Academy of the AACC on the use of cardiac troponin in coronary disease
- Updating cardiac troponin and natriuretic peptide assay tables by both manufacturer claims and from peer-reviewed literature
- Distribution of educational posters and mouse-pads addressing high sensitivity cardiac troponin assays at IFCC meetings in 2017
05 December, 2019 On behalf of the members of the IFCC Committee on Clinical Applications of Cardiac Bio-Markers (C-CB), we post our fourth 2019 set of tables, updating the analytical characteristics of contemporary, point of care (POC) and high sensitivity (hs) cardiac troponin I and T assays; as provided by the manufacturer to the C-CB. Please note that these tables represent information that were completed by the manufacturer. If after posting, the manufacturer notes any error, please email me ASAP, so these can be corrected. Also note that manufacturers may have submitted assays they claim to be ‘high sensitivity’ that do not meet the IFCC requirements of: a) ≤10% CV at the 99th percentile and b) ≥50% measurable concentrations ≥ LoD (Apple FS, Jaffe AS, Collinson P, Mockel M, Ordonez-Llanos J, Lindahl B, Hollander J, Plebani M, Than M, Chann MHM, on behalf of the IFCC Task Force on Clinical Applications of Cardiac Bio-Markers. IFCC educational materials on selected analytical and clinical applications of high-sensitivity cardiac troponin assays. Clin Biochem 2015: 2015;48:201-203). As a Committee we have not altered their information. It is the plan of the IFCC C-CB to update these tables every 6 months. Therefore, we encourage both industry and investigators to email me any new or updated assay information based on research publications or regulatory approval package inserts, to assist in our table updates. Peace Fred Apple PhD, Chair IFCC C-CB apple004@umn.edu 28 August 2020 We post our first table updates for the 21st century. We apologize for the delay since last updated, as the COVID-19 global pandemic has affected all our lives in so many ways. We hope all are well and safe and these updates continue to assist your practices. I thank Amy Saenger PhD for her dedication to this project. Peace Fred Apple PhD, Chair IFCC C-CB Click on the titles to download the documents: |
Tables posted 28 August 2020:
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List of Corresponding Members, nominated by National Societies
Name | Full and Affiliate Member Societies |
| Caroline Le Goff | Royal Belgian Society of Laboratory Medicine (RBSLM) |
| Galina Zemtsovskaja | Estonian Society of Laboratory Medicine |
| Hannsjoerg Baum | Deutsche Gesellschaft für Klinische Chemie und Laboratoriumsmedizin e.V. (DGKL) |
| Monica Mion | Italian Society of Clinical Chemistry and Clinical Molecular Biology (SIBioC) |
| Hiroshi Yoshida | Japan Society of Clinical Chemistry (JSCC) |
| Dovile Karciauskaite | Lithuanian Society of Laboratory Medicine |
| Steven Meex | Nederlandse Vereniging voor Klinische Chemie en Laboratoriumgeneeskunde (NVKC) |
| Akinosun Bayo | Association of Clinical Chemists Nigeria (ACCN) |
| Lakminda Thilakarathna | Association for Clinical Biochemistry, Sri Lanka |
| Aylin Hakligor | Turkish Biochemical Society (TBS) |
List of Corresponding Members, nominated by Corporate Members
| Name | Corporate members |
| Tricia Ravalico | ABBOTT Laboratories |
| Adam Moss | ABBOTT APOC |
| Lindsay Sun | BECKMAN COULTER |
| Robert Zuk | ET HEALTHCARE |
| Geert Jannes | FUJIREBIO Europe |
| Frank Ocklenburg | MITSUBISHI CHEMICAL EUROPE |
| Jakob Eriksen | RADIOMETER |
| Gesa Ines Albert | ROCHE Diagnostics |
| Kalen Olson | SIEMENS Healthineers |
Corporate Members Support
| Corporate members | LEVEL SUPPORT |
| ABBOTT | PLATINUM LEVEL SUPPORT |
| ALERE | CRYSTAL LEVEL SUPPORT |
| ET HEALTHCARE | BRONZE LEVEL SUPPORT |
| ORTHO CLINICAL DIAGNOSTICS | GOLD LEVEL SUPPORT |
| RADIOMETER | BRONZE LEVEL SUPPORT |
| SIEMENS Healthineers | GOLD LEVEL SUPPORT |
| BECKMAN COULTER | SILVER LEVEL SUPPORT |
| ROCHE | SILVER LEVEL SUPPORT |
List of addresses
ChairDr Fred APPLE |
Members | |
Dr Peter KAVSAK | Dr Guillaume LEFEVRE |
Dr Kari PULKKI | Dr Amy SAENGER |
| Dr Richard BODY Emergency Medicine Research Office, Emergency Department, Manchester Royal Infirmary, Oxford Road, Manchester, M13 9WL, UK | Dr Su Ping Carolyn LAM National Heart Centre Singapore SingHealth Duke-NUS Cardiovascular Academic Clinical Programme and Department of Cardiology 5 Hospital Drive Singapore 169609 - SG |
Dr Torbjørn OMLAND | |
Consultants | |
Dr. Paul O. COLLISON | Dr. Allan JAFFE Cardiovascular Division, Gonda 5 Mayo Clinic 200 First Street SW Rochester - MN 55905 USA Tel.: +1 507 284 1648 |
Dr. Jordi ORDÓÑEZ-LLANOS |