Advancing excellence in laboratory medicine for better healthcare worldwide

Committee on Clinical Applications of Cardiac Bio-Markers (C-CB)

Membership

NamePositionCountryTermTime in Office
F. AppleChairUS1st2017 01 - 2019 12
P. KavsakMemberCA1st2017 01 - 2019 12
G. LefevreMemberFR1st2017 01 - 2019 12
K. PulkkiMemberFI1st2017 01 - 2019 12
A. SaengerMemberUS1st2017 01 - 2019 12
R. BodyMemberUK1st2017 01 - 2019 12
SPC LamMemberSG1st2017 01 - 2019 12
T. OmlandMemberNO1st2017 01 - 2019 12
P. CollinsonConsultantUK
A. JaffeConsultantUS
J. Ordoñez-LlanosConsultantES

Terms of Reference

  • Education; Established and novel cardiac biomarkers
  • Biochemistry of cardiac biomarkers
  • Clinical use of cardiac biomarkers: risk stratification, diagnostics, therapy
  • Laboratory issues on cardiac biomarkers: 99th percentiles, delta values, biological variation, quality specifications of assays

Current Projects

  • Development of educational materials about high-sensitivity, contemporary and point of care cardiac troponin assay use in clinical practice.
  • Development of educational materials about natriuretic peptide assay use in clinical practice
  • Development of educational expert opinion materials in collaboration with The Academy of the AACC on the use of cardiac troponin in coronary disease
  • Updating cardiac troponin and natriuretic peptide assay tables by both manufacturer claims and from peer-reviewed literature
  • Distribution of educational posters and mouse-pads addressing high sensitivity cardiac troponin assays at IFCC meetings in 2017

10 June, 2019

On behalf of the members of the IFCC Committee on Clinical Applications of Cardiac Bio-Markers (C-CB), we post our third 2019 set of tables, updating the analytical characteristics of contemporary, point of care (POC) and high sensitivity (hs) cardiac troponin I and T assays; as provided by the manufacturer to the C-CB.

Please note that these tables represent information that were completed by the manufacturer. If after posting, the manufacturer notes any error, please email me ASAP, so these can be corrected. Also note that manufacturers may have submitted assays they claim to be ‘high sensitivity’ that do not meet the IFCC requirements of: a) ≤10% CV at the 99th percentile and b) ≥50% measurable concentrations ≥ LoD (Apple FS, Jaffe AS, Collinson P, Mockel M, Ordonez-Llanos J, Lindahl B, Hollander J, Plebani M, Than M, Chann MHM, on behalf of the IFCC Task Force on Clinical Applications of Cardiac Bio-Markers. IFCC educational materials on selected analytical and clinical applications of high-sensitivity cardiac troponin assays. Clin Biochem 2015: 2015;48:201-203).

As a Committee we have not altered their information.

It is the plan of the IFCC C-CB to update these tables every 6 months. Therefore, we encourage both industry and investigators to email me any new or updated assay information based on research publications or regulatory approval package inserts, to assist in our table updates.

Peace

Fred Apple PhD, Chair IFCC C-CB

apple004@umn.edu

Click on the titles to download the documents:

Tables posted 10 June 2019:

List of Corresponding Members, nominated by National Societies

Name

Full and Affiliate Member Societies
Caroline Le GoffRoyal Belgian Society of Laboratory Medicine (RBSLM)
Galina ZemtsovskajaEstonian Society of Laboratory Medicine
Hannsjoerg BaumDeutsche Gesellschaft für Klinische Chemie und Laboratoriumsmedizin e.V. (DGKL)
Monica MionItalian Society of Clinical Chemistry and Clinical Molecular Biology (SIBioC)
Hiroshi YoshidaJapan Society of Clinical Chemistry (JSCC)
Dovile KarciauskaiteLithuanian Society of Laboratory Medicine
Akinosun BayoAssociation of Clinical Chemists Nigeria (ACCN)
Lakminda ThilakarathnaAssociation for Clinical Biochemistry, Sri Lanka
Aylin  Hakligor

Turkish Biochemical Society (TBS)

List of Corresponding Members, nominated by Corporate Members

NameCorporate members
Tricia RavalicoABBOTT Laboratories
Adam MossABBOTT APOC
Lindsay SunBECKMAN COULTER
Robert ZukET HEALTHCARE
Geert JannesFUJIREBIO Europe
Frank Ocklenburg     MITSUBISHI CHEMICAL EUROPE
Jakob EriksenRADIOMETER
Gesa Ines AlbertROCHE Diagnostics
Kalen OlsonSIEMENS Healthineers


Corporate Members Support

Corporate membersLEVEL SUPPORT
ABBOTTPLATINUM LEVEL SUPPORT
ALERECRYSTAL LEVEL SUPPORT
ET HEALTHCAREBRONZE LEVEL SUPPORT
ORTHO CLINICAL DIAGNOSTICSGOLD LEVEL SUPPORT
RADIOMETERBRONZE LEVEL SUPPORT
SIEMENS HealthineersGOLD LEVEL SUPPORT
BECKMAN COULTERSILVER LEVEL SUPPORT
ROCHESILVER LEVEL SUPPORT


List of addresses

Chair

Dr Fred APPLE
Hennepin County Medical Center
Professor, Laboratory Medicine and Pathology
University of Minnesota - School of Medicine
701 Park Avenue Clinical Labs P4
Minneapolis MN 55415 US
Tel.: +1  612 873 3324
email: apple004@umn.edu

Members

 

Dr Peter KAVSAK
McMaster University and Hamilton Health Sciences
Juravinski Hospital and Cancer Center
711 Concession Rd
L8V 1C3 Hamilton - CA

Dr Guillaume LEFEVRE
Biochimie & Hormonologie
Hôpital Tenon  AP-HP
Hôpitaux Universitaires de l’Est Parisien (HUEP)
4, rue de la Chine  75970 PARIS CEDEX 20 - FR

Dr Kari PULKKI
Department of Clinical Chemistry,
University of Eastern Finland and Eastern Finland Laboratory Centre,
PO Box 1627,
FI-70211 Kuopio, Finland

Dr Amy SAENGER 
University of Minnesota
Department of Laboratory Medicine and Pathology
425 Delaware St. SE, Mayo Building MMC609
Minneapolis, MN 55455, US

Dr Richard BODY
Emergency Medicine Research Office,
Emergency Department,
Manchester Royal Infirmary,
Oxford Road,
Manchester,
M13 9WL, UK
Dr Su Ping Carolyn LAM
National Heart Centre Singapore
SingHealth Duke-NUS Cardiovascular Academic Clinical Programme
and Department of Cardiology
5 Hospital Drive
Singapore 169609 - SG

Dr Torbjørn OMLAND
Akershus Universitetssykehus
1478 Lørenskog - NO

Consultants

Dr. Paul O. COLLISON
Department of Chemical Pathology
2nd Floor Jenner Wing
St George's Hospital
Blackshaw Road
London SW17 0QT UK
Tel.: +44  208 725 5934

Dr. Allan JAFFE
Cardiovascular Division, Gonda 5
Mayo Clinic
200 First Street SW
Rochester - MN 55905
USA 
Tel.: +1 507 284 1648

Dr. Jordi ORDÓÑEZ-LLANOS
Senior Consultant, Biochemistry Dept.
Hospital de Sant Pau
Professor of Clinical Biochemistry
Universitat Autònoma
Barcelona - Spain
Tel.: +34 935537359

 
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