Advancing excellence in laboratory medicine for better healthcare worldwide

Nomenclature, Properties and Units (C-NPU) in collaboration with International Union of Pure and Applied Chemistry (IUPAC)

The IFCC-IUPAC coding system

Provides a terminology for Properties and Units in the Clinical Laboratory Sciences. The availability of electronic patient records would greatly increase the quality of health care, reduce health care cost and facilitate epidemiological surveys to the benefit of patient's worldwide. In developing a generalized architectural build up and adherent structures, there is a need for systems and schemes in each of the medical domains to support and populate the electronic patient record. In the domain of clinical laboratory medicine the guidelines from IFCC-IUPAC on the structuring of properties, on kind-of-properties and on units are needed if a coherent system with global acceptance is to be worked out.

The C-NPU maintains the website below to make available the complete contents of the generic C-NPU database for electronic downloading. The website outlines the structure of the NPU terminology and provides instructions for using the database. NPU Laboratory Terminology website: www.npu-terminology.org

A current version of the C-NPU database (in English) is also available for direct download

A searchable database can be accessed by clicking on this link

(last update October 2019)

IFCC-IUPAC / C-NPU documents

The background for the IFCC-IUPAC coding system for laboratory investigations is described in the publications.
Also a series of documents from the Word Health Organization, from the European Standardization Committee and many international organizations have been adhered to in the course of the project, in particular for coding of concepts defined by these organizations e.g. CAS, ATCC, UMLS, CLSI, UMD, INN, ISTH, OMIM.

C-NPU Publications

  • "An Ontology of Property for Physical Chemical and Biological Systems", by Dr. René Dybkaer: http://ontology.iupac.org/

  • Published papers on Properties and Units in the Clinical Laboratory Sciences include:

  1. IUPAC-IFCC (International Union of Pure and Applied Chemistry & International Federation of Clinical Chemistry, Commission on Clinical Chemistry), 1967. Quantities and units in clinical chemistry. Recommendation 1966. Prepared for publication by Dybkær R, Jørgensen K. Copenhagen: Munksgaard.
  2. J.C.Riggs, S.S.Brown, R.Dybkær, and H.Olesen,: Compendium of terminology and nomenclature of properties in clinical laboratory sciences ('The Silver Book'). IUPAC: Oxford: Blackwell Science, 1995, 290 pp. a volume in the IUPAC Nomenclature Books series ('The Silver Book'). Synopsis
  3. H.P. Lehmann, X.Fuentes-Arderiu and L.F.Bertello, Glossary of Terms in quantities and units in clinical Chemistry, Pure and Applied Chemistry 1996:68:957-1000.
  4. EN 1614:2006  Health Informatics – Representation of dedicated kinds of property in laboratory medicine

An extensive list of scientific publications from the joint IFCC-IUPAC Committee is available at http://www.npu-terminology.org/

Committee on Nomenclature for Properties and Units (C-NPU), in collaboration with International Union of Pure and Applied Chemistry (IUPAC)

Membership

NamePositionCountryTermTime in Office
K. ToskaChairNO1st2018 03 - 2020 12
K. FurutaMemberJP1st2019 02 - 2021 12
Y.B.L. HansenMemberDK1st2017 03 - 2019 12
E. van der HagenMemberNL1st2018 02 - 2020 12
To be appointedMember

Terms of Reference

  • To continuously provide advice in relation to the management, updating and publishing of NPU terminology.
  • To make recommendations on NPU for reporting clinical laboratory data that conform to or adapt current standards of authoritative organizations, and that will improve their utilization for health care.
  • To provide a connection with other organizations concerned with NPU, such as the Bureau International des Poids et Mesures (BIPM), the European Committee for Standardization (CEN) and the International Organization for Standardization (ISO), and, by extension, clinical laboratory sciences societies, such as the International Union of Pure and Applied Chemistry (IUPAC), and the in vitro diagnostics industry, to ensure that problems encountered by health care professionals in the area of NPU are considered by those organizations.
  • To act as a consultant group on NPU in clinical chemistry and, by extension, in the rest of clinical laboratory sciences to international scientific panels, regional and national clinical laboratory sciences organizations, editors of scientific journals, manufacturers of clinical laboratory instrumentation and products, and to individual clinical laboratory professionals and other health care professionals.
  • To report and offer advice to the SD Chair and the SD Executive Committee on matters concerning NPU in all its aspects (all items above).

Current Projects

  • Transfer of the NPU generic database to IFCC site : help and advice on training the future IFCC NPU database manager(s) in relation to the installation, updating and management of the database, and on its relationship relations with other national versions.
  • Mapping of the IFCC-IUPAC laboratory coding system to SNOMED CT.
  • Securing and structural updating of information in the NPU coding system and its environment.
  • Development of an international vocabulary for nominal examinations in scientific communication.

List of Corresponding Members, nominated by National Societies

NameFull and Affiliate Member Societies
Gilbert HillCanadian Society of Clinical Chemistry (CSCC)
Ulla Magdal PetersenDanish Society of Clinical Biochemsitry (DSKB)
Aracelis GermánColegio Dominicano de Bionalistas (CODOBIO)
Alessandro MarocchiItalian Society of Clinical Chemistry and Clinical Molecular Biology (SIBioC)
Naohito Ishii
Japan Society of Clinical Chemistry (JSCC)
Dalius VitkusLithuanian Society of Laboratory Medicine
Aaron OjuleAssociation of Clinical Chemists Nigeria (ACCN)
Valentina NaztmutdinovaAssociation of Laboratory Specialists and Organizations
«Federation of laboratory medicine» (FLM) - Russia
Nada Majkic-SinghSociety of Medical Biochemists of Serbia (DMBS)
Ariadna Padró-MiquelSociedad Española de Bioquímica Clínica y Patología Molecular (SEQC)
Murat BolayirliTurkish Biochemical Society (TBS)
Carlos LacavaAsociación Bioquímica Uruguaya (ABU)
Sridevi DevarajAmerican Association for Clinical Chemistry (AACC)

Committee Chair's contact:

Dr. Karin Toska
Department of Medical Biochemistry
Oslo University Hospital
Ullevål sykehus
PO Box 4956 Nydalen
0424 Oslo
Norway
E-mail: karin.toska@gmail.com

 
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