Advancing excellence in laboratory medicine for better healthcare worldwide

Harmonisation of Autoantibody Tests (WG-HAT)


NamePositionCountryTermTime in Office
J. SheldonChairUK2nd2013 01 - 2015 12
P.L. MeroniMemberIT
I. ZegersMemberBE

Terms of Reference

  • To evaluate what are the main causes of variability for a number of diagnostically critical autoantibody measurements.
  • To identify autoantibodies where a common calibrator could reduce the inter-assay variability
  • To identify or produce commutable reference materials that could be used as interim calibration material for autoantibody assays.
  • To produce well-characterised pure antibody preparations with known concentration and identity and use these to transfer values to a matrix preparation.

Current projects

  • Evaluation of EQA data to identify the autoantibody tests with the potential for harmonisation of results.
  • Gathering a comprehensive data base of the assay characteristics of the currently available autoimmune serology methods.
  • Identifying existing materials that could be used to assess interassay variability and possibly be used as interim calibration material.
  • Defining the requirements for a calibration material for autoimmune serology.

List of Corresponding Members, nominated by National Societies

NameFull and Affiliate Member Societies
David GillisAustralasian Association of Clinical Biochemists
Xavier BossouitSociété Belge de Chimie Clinique (SBCC)
Pierre CarayonSociété Française de Biologie Clinique (SFBC)
Rudolf GruberDeutsche Vereinte Gesellschaft für Klinische Chemie und Laboratoriumsmedizin e.V. (DGKL)
Tímea BerkiHungarian Society of Laboratory Medicine (MLDT)
Naoya InoueJapan Society of Clinical Chemistry (JSCC)
Loreta BagdonaiteLithuanian Society of Laboratory Medicine
Gabriel OyeyinkaAssociation of Clinical Chemists Nigeria (ACCN)
Neslihan BukanTurkish Biochemical Society (TBS)

List of Corresponding Members, nominated by Corporate Members

NameCorporate members
Michael RottmannROCHE Diagnostics GmbH

Working Group Chair's contact

Dr. Joanna SHELDON
Protein Reference unit
St. George's Hospital
Blackshaw Road
London SW17 0NH
Te.: +44 (0) 208 725 5752
Fax: +44 (0) 208 725 0025

Website developed by Insoft