Advancing excellence in laboratory medicine for better healthcare worldwide

Standardisation of Insulin Assays (WG-SIA) - in collaboration with ADA/EASD


M. SteffesCo-ChairUS
J. SeegmillerCo-ChairUS
D. HolmesMemberCA
R. LittleMemberUS
M. McPhaulMemberUS
G. MillerMemberUS
H. RitzénMemberSE
D. SacksMemberUS
G. WarkMemberUK
B. AkolkarConsultant  / NIH NIDDKUS
K. Van UytfangheConsultantBE

Terms of Reference

  • To improve the standardization of assays for insulin by the development of a candidate reference method and materials.

Current Projects

  • The development of a reference method for the measurement of insulin by electrospray ionization-isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC/tandem MS).
  • Establishment of the suitability or otherwise of a lyophilized recombinant human insulin preparation as a primary reference material with appropriate properties
  • Establishment of the performance of commercially available insulin assays compared to the ID-LC/tandem MS method using single donation samples and the effect of using a common primary reference material or serum pools on between method agreement.
  • Determination of the effect of freeze/thawing on measured insulin (a requirement to establish the validity of materials for 3 above).

List of Corresponding Members, nominated by National Societies

NameFull and Affiliate Member Societies
Paul GlendenningAustralasian Association for Clinical Biochemistry and Laboratory Medicine (AACB)
Syuu MeguroJapan Society of Clinical Chemistry (JSCC)
Andrejus CojLithuanian Society of Laboratory Medicine
Fayeofori AbbiyesukuAssociation of Clinical Chemists Nigeria (ACCN)
Oguzhan ZengiTurkish Biochemical Society (TBS)
Gary MyersAmerican Association for Clinical Chemistry

List of Corresponding Members, nominated by Corporate Members

NameCorporate members
Tanja DubravcicSIEMENS

Working Group Co-Chairs' contacts

Dr. Michael STEFFES
Institute University of Minnesota
3098 East Castle Danger Road
Two Harbors, MN 55616

Assistant Professor
Department of Laboratory Medicine and Pathology
University of Minnesota
420 Delaware Street SE
Mayo Building, Rm: D185
Minneapolis, MN 55455

Website developed by Insoft