2019 Publications of Interest

C-NPU - Nomenclature, Properties and Units -  Joint Committee of IFCC/IUPAC

1. Young Bae Lee Hansen: Recommendations on measurement units – why and how: eJIFCC Volume 30 no 3 – 2019

C-TLM - Traceability in Laboratory Medicine

1. The results of RELA2019 have been evaluated and published http://www.dgkl-rfb.de:81

C-HAT - Harmonization of Autoimmune Tests

1. Monogioudi E; Zegers I; Hutu DP; Sheldon J;  Schimmel H; Meroni PL. Certified Reference Material against PR3 ANCA IgG autoantibodies. From development to certification. Clin Chem Lab Med. 2019 Jul 26;57(8):1197-1206. doi: 10.1515/cclm-2018-1095.

C-BM - Bone Metabolism

1. Etienne Cavalier, Richard Eastell, Niklas Rye Jørgensen, Konstantinos Makris, Symeon Tournis, Samuel Vasikaran, John A. Kanis, Cyrus Cooper, Hans Pottel and Howard A. Morris, on behalf of the IFCC-IOF Joint Committee for Bone Metabolism (C-BM), “A multicenter study to evaluate harmonization of assays for N-terminal propeptide of type I procollagen (PINP): a report from the IFCC-IOF Joint Committee for Bone Metabolism”. Clin Chem Lab Med 2019; 57(10): 1546–1555.
2. Abstract on “PINP harmonization: a report of the IOF-IFCC Committee for Bone metabolism” presented during IOF meeting in Paris on April 5th

WG-SAU - Standardization of Albumin Assay in Urine – in collaboration with NKDEP

1. Miller WG, Bachmann LM, Fleming JK, Delanghe JR, Parsa A, Narva AS. Recommendations for reporting low and high values for urinary albumin and total protein [Letter to the Editor]. Clin Chem 2019; 65(2):349-350.

WG-APO MS - Apolipoproteins by Mass Spectrometry

The group aims for submission of the following manuscripts in 2020:

1. A manuscript will be a technical note or letter on the improved digestion of apolipoproteins using a combination of lysC and trypsin. This manuscript will summarize the findings and evidence gathered by the three reference labs (LUMC, CDC and UKL).
2. A second manuscript that will be in the preparation phase by the end of 2020 is the development of a harmonized LC-MS based reference method, including results from the planned ring trials.

Members of the group have participated in several related publications:

1. Orsi FA, Lijfering WM, Van der Laarse A, Ruhaak LR, Rosendaal FR, Cannegieter SC, Cobbaert C. Association of apolipoproteins C-I, C-II, C-III and E with coagulation markers and venous thromboembolism risk. Clin Epidemiol. 2019 https://doi.org/ 10.2147/CLEP.S196266.
2. Ruhaak LR, Van der Laarse A, Cobbaert CM. Apolipoprotein profiling as a personalized approach to the diagnosis and treatment of dyslipidaemia. Annals of Clinical Biochemistry. 2019 https://doi.org/10.1177/0004563219827620
3. Dittrich J, Beutner F, Teren A, Thiery J, Burkhardt R, Scholz M, Ceglarek U. Plasma levels of apolipoproteins C-III, A-IV, and E are independently associated with stable atherosclerotic cardiovascular disease. Atherosclerosis. 2019 Feb;281:17-24. https://doi.org/10.1016/j. atherosclerosis.2018.11.006